中国睡眠研究会官方指导

《SLEEP中文版》第6卷第1期

原文作者

Bastien Lechat, Kristy Hansen, Gorica Micic, Felix Decup, Claire Dunbar, Tessa Liebich, Peter Catcheside,  and Branko Zajamsek

翻译专家

程金湘

审校专家

师  乐

摘要

研究目的：本研究的主要目的是研究风电场和道路交通噪声的声压水平（Sound Pressure Levels，SPLs）和K复合波发生概率之间的剂量—反应关系。次要目的是比较人工评分的脑电图觉醒和觉醒时K复合波的剂量反应。

方法：25名受试者在实验室接受了多导睡眠记录和睡眠期间的噪音暴露。在确定的N2或更深的睡眠期间，持续随机播放了在33 ~ 48 dBA之间的6个SPLs持续20秒的风电场和道路交通噪声录音。噪音周期与23 dBA的背景噪音周期分开。使用一种经过验证的算法对K复合波进行评分。比较了控制噪声声压级、主观噪声敏感度和测量听力灵敏度的噪声类型的K复合波发生概率。

研究结果：在N2睡眠中，噪音诱导的K复合波，SPLs最低可至33 dBA[比值比，33 dBA vs. 23 dBA，平均值（95%置信区间）；1.75（1.16 ~ 2.66）]，并随着SPL的增加而增加。在N2睡眠中脑电图觉醒和清醒仅与高于39 dBA的噪声相关。K复合波对噪声产生反应的可能性是脑电图觉醒或清醒的2倍。主观噪声敏感度和听敏度与K复合波的发生有关，但与唤醒或觉醒无关。噪声类型对K复合波，脑电图觉醒或清醒反应没有明显影响。

结论：这些研究表明K复合波是一项对睡眠中环境噪声感觉处理的敏感标志，而听力灵敏度的提高和自我报告的噪声敏感性的降低增加了K复合波的概率。

关键词：环境噪声；K复合波；噪声敏感性；睡眠碎片化；睡眠中断；觉醒；清醒；深度学习；人工智能

图表

Figure 1. A, experimental protocol showing an example of block-randomised noise stimuli. B, experimental set-up. C, noise characteristics and measurement locations. Noise power spectral density were measured in the laboratory at the participants' head location, over a 20 seconds period.

Table 1. Participant characteristics stratifed by noise sensitivity group. Data are presented in n (%) for categorical variable, median [IQR] for non-normally distributed variables, and mean (SD) for normally distributed continuous variable

Figure 2. Association between noise SPL and K-complex response in N2 sleep. A, probability of occurrence of a K-complex at a given noise level. B, odds ratio (95% CI) of evoking a K-complex at a given SPL compared to background noise.

Figure 3. Association between noise SPL and the K-complex response in N2 sleep for participants with hearing thresholds ≤3.9 dB HL (orange) or >3.9 dB HL (purple). A, probability of occurrence of a K-complex at a given noise level. B and C, odds ratio (95% CI) of evoking a K-complex at a given SPL compared to background noise.

Figure 4. Association between noise SPL and the K-complex response in N2 sleep for participants with aWeinstein noise sensitivity score ≤54 (orange) or >54 (purple). A, probability of occurrence of a K-complex at a given noise level. B and C, odds ratio (95% CI) of evoking a K-complex at a given SPL compared to background noise.

Figure 5. Association between noise SPL and arousal/awakening response in N2 sleep. A, probability of occurrence of arousal/awakening at a given noise level. B, odds ratio (95% CI) of evoking arousal/awakening at a given SPL compared to background noise.

来源：SLEEP中文版第6卷第1期摘要3

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《SLEEP中文版》编委会云集国内睡眠领域众多优秀专家、学者。各位编委以极高的热情和严谨的专业精神投入到论文的翻译审校中，经过数月辛勤筹备与精心打磨，《SLEEP中文版》第七期电子版将陆续发布！

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杂志简介

SLEEP 杂志创刊于 1978 年，是美国睡眠研究学会的官方期刊，由牛津大学出版社出版，在国际睡眠研究领域期刊中排名第一，五年学术影响因子高达 6.0分，是一本高质量、高水平的睡眠医学专业杂志。

原标题：【第7期 摘要】K复合波是睡眠过程中与噪声相关的感觉处理的敏感标志：一项初步研究

本文来源：SLEEP前沿（ID：gh_b460d40d8213），转载引用请注明原出处